Journal of Health and Safety at Work

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Introduction: Nowadays, many modern industries require an environment with no contamination by particles and bacteria. An enclosed clean room environment is a place where parameters such as airborne particles, temperature, humidity, air pressure and air flow pattern is controlled. The aim of this study was to evaluate functional parameters of a clean room  in a selected pharmaceutical industry.  

Material and Method: This study was an experimental study conducted in 2015 in a pharmaceutical industry.  The air flow rate and flow rate with airflow capture hood was used and multi sensor devices for measuring temperature, humidity and pressure of multi-sensor device. HEPA filter leakage test and counting concentration of particles in the cleanroom was done according to the ISO 14644 – 3(2005) standards using aerosol photometer and aerosol generator. In this study, 6 clean room relating to the 3 cleanliness classes B, C and D (in accordance with standard EU GMP) were evaluated. Meanwhile, both the 2 and 3-dimensional flow model using Computational Fluid Dynamics Software was simulated in this study.   

Result: Measuring the parameters flow rate and air velocity, temperature (average temperature 20 ° C), relative humidity (below 50%), pressure (pressure less than 15 psi) for every three classes of cleanliness are all acceptable and less than the proposed standard. Furthermore, the results of modelling showed that the pattern of air flow in the room is correct paths in circulation. In the case of leakage test filters, the filter 29 filters tested 5 was leaking and ultimately determine the HEPA filters remove particles that average efficiency is 99.99%.

Conclusion: This study showed that the high volume and good quality of air entering the clean room affect the optimal efficiency and air flow rate, pressure drop and air penetration of the HEPA filters Also, the results of study show that the concentration of airborne particles in clean room is depend on the air flow rate and speed and adopting a good air flow pattern will affect the particle concentration.

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Introduction: Occupational health is one of the important issues that can affect productivity and economic development of an organization. This study aimed to determine the effect of didactic interventional Ergonomic-Safety program on workers’ productivity of an assembling industry.
Methods and Materials: This interventional study was conducted on 54 workers of assembling part of an electronic industry. Firstly, QEC method was used for Ergonomic assessment of work place and Hersey-Goldsmith questionnaire was applied for assessment of productivity. Then a comprehensive program was provided using findings of first stage assessment and identifying of existing failures. Second assessment of Ergonomic condition and productivity was done again by using QEC method and Hersey-Goldsmith questionnaire within three month of interventions. Data was analyzed by using of R software.
Results: Mean total productivity score and mean whole body score of QEC were 75.24 and 99.40 in before intervention phase respectively. In after intervention phase, Mean total productivity score and mean whole body score of QEC were 80.16 and 97.92 respectively. Data analysis by paired-samples t-test shows that difference of productivity score in before and after intervention phase was significant (P-value˂0.05). But difference of whole body score of QEC score in before and after intervention phase was not significant (P-value>0.05).
Conclusion: Accomplishment of Ergonomic-Safety intervention had a positive effect on productivity score whereas had not significant effect on general condition of body limbs.